Franklin Douglis, MD

The Ear Nose Throat
Allergy Sinus & Snoring Center

Semagultide text with tape measure Semaglutide FAQ

What is Semaglutide?

Semaglutide is a revolutionary GLP-1 receptor agonist that was originally developed for patients with Type 2 diabetes, but when providers and pharmaceutical developers noticed how much weight their patients were losing, they began to study semaglutide exclusively for weight loss. A series of clinical trials known as the STEP clinical trials demonstrated that almost 90% of patients lost 5% or more of their body weight. There is no other weight loss drug on the market that compares. In June of 2022, the FDA approved semaglutide for weight loss.

How does Semaglutide work?

Semaglutide acts like GLP-1 (a gut hormone) to: Increase insulin production Decrease glucagon synthesis Delay gastric emptying Suppress hunger. It signals your brain that you are full so you can lose weight without feeling like you are depriving yourself.

What are potential side effects?

Commonly reported GI side effects – nausea, vomiting, diarrhea, constipation, abdominal pain Site reactions Fatigue Headaches.

Who is not a candidate for Semaglutide?

  • Under 18 years old
  • Pregnant/breastfeeding
  • Type 1 diabetes mellitus Hypersensitivity to semaglutide or any components of this medication
  • Personal or family history of medullary thyroid carcinoma
  • History of multiple endocrine neoplasia syndrome History of pancreatitis
  • End stage renal disease (on dialysis)
  • BMI less than 25
  • Type 2 diabetic patients that are on insulin or a sulfonylurea
  • Patients with diabetic retinopathy
  • Patients that are on several antihypertensive medications

Who is a candidate?

  • Everyone else
Health history, medications and body weight information will be carefully reviewed by a licensed provider to determine each candidate’s eligibility.